22 Projects | 12 Researchers | $2,931,470 Invested
2019
Trustees of Columbia University in the City of New York
Yaakov Stern, PhD
1st Workshop on Research Definitions for Reserve and Resilience in Cognitive Aging and Dementia
2018
Trustees of Columbia University in the City of New York
Brent Stockwell, PhD
Evaluation and development of optimized PDI modulators for AD
2016
Trustees of Columbia University in the City of New York
Ottavio Arancio, MD, PhD
A novel isoform selective kinase inhibitor candidate with in vivo efficacy in two AD models: proposal for GLP tox package for phase 1 IND
2015
Trustees of Columbia University in the City of New York
Brent Stockwell, PhD
Protein disulfide isomerase (PDI) inhibitors as neuroprotective agents for Alzheimer's disease.
2014
Trustees of Columbia University in the City of New York
Daniel Javitt, MD, PhD
Neurophysiological biomarkers for AD drug development
2013
Trustees of Columbia University in the City of New York
Tae-Wan Kim, PhD
Screening for small molecule modulators of tau in stem cell-derived primary neurons
2012
Trustees of Columbia University in the City of New York
Wai Haung Yu, PhD
Development of small molecule enhancers of autophagy for the clearance of protein aggregates and treatment of FTD
2011
Trustees of Columbia University in the City of New York
Lawrence Honig, MD, PhD
Magnetic Resonance Spectroscopy (MRS) to assess progression of Alzheimer Disease (AD)
2011
Trustees of Columbia University in the City of New York
Eric Schon, PhD
Mitochondria-associated membranes in the pathogenesis of Alzheimer's disease: a new target for drug discovery
2011
Trustees of Columbia University in the City of New York
Tae-Wan Kim, PhD
Development of screening assays for tauopathy in stem-cell derived neurons
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