Funding Opportunities

The Alzheimer's Drug Discovery Foundation (ADDF) funds four different categories of research:

  • Drug discovery and preclinical development
  • Early detection
  • Clinical trials
  • Prevention

The ADDF is interested in novel targets and therapeutic approaches for Alzheimer’s disease, related dementias and cognitive aging. These areas include, but are not limited to:

  • Energy utilization/mitochondria function
  • Insulin sensitivity
  • Protein degradation/autophagy
  • ApoE function and cholesterol metabolism
  • Vesicular trafficking
  • Inflammatory pathways
  • Synaptic function/morphology
  • Calcium regulation
  • Myelin changes
  • Ischemia and oxidative stress
  • Vascular injury
  • Blood-brain barrier interface
  • Translatable biomarkers.

The ADDF no longer funds anti-amyloid approaches and has limited interest in funding cholinesterase inhibitor programs. For more information on Alzheimer's funding opportunities, please see our Request for Proposals.

Questions and Comments

The ADDF welcomes potential applicants to direct proposal ideas, questions and comments to:

For more information on the application process or questions regarding an existing application, please contact Danielle Popow, Grants Coordinator. 

Apply for Funding

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