OUR PORTFOLIO

Our portfolio includes grants and mission-related investments supporting Alzheimer’s drugs in development, biomarkers, prevention programs, and other projects designed to build the capacity of the field. You can explore the programs we have supported using the filter and “Search Database” options in the sidebar.

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Organization: Cleveland Clinic Foundation

5 Projects | 3 Researchers | $3,086,613 Invested

2023

Cleveland Clinic Foundation

Dianne Perez, PhD

IND-Enabling Studies for a Novel Positive Allosteric Modulator of the Alpha1A-Adrenergic Receptor to Treat Alzheimer’s Disease

  • Funding Amount: $1,828,343
  • Organization Type: Academic/Nonprofit
  • Program: Clinical
  • Target: Synaptic Activity and Neurotransmitters
  • Status: Active

2018

Cleveland Clinic Foundation

Dianne Perez, PhD

Optimization of Novel Positive Allosteric Modulators of the Alpha1A-Adrenergic Receptor to treat Alzheimer's Disease

  • Funding Amount: $494,440
  • Organization Type: Academic/Nonprofit
  • Program: Drug Discovery
  • Target: Synaptic Activity and Neurotransmitters
  • Status: Closed

2014

Cleveland Clinic Foundation

Mohamed Naguib, MB, BCh, MSc, FCARCSI, MD

Prevention of glial neuroinflammation in Alzheimer's Disease -- Targeting a novel receptor to preserve neurocognitive function

  • Funding Amount: $257,700
  • Organization Type: Academic/Nonprofit
  • Program: Clinical
  • Target: Neuroinflammation
  • Status: Closed

2003

Cleveland Clinic Foundation

Jonathan Smith, PhD

Drug Discovery: Estrogen Related Compounds in Mouse Models of Alzheimer's Disease

  • Funding Amount: $90,000
  • Organization Type: Academic/Nonprofit
  • Program: Drug Discovery
  • Status: Closed

1999

Cleveland Clinic Foundation

Jonathan Smith, PhD

Estrogen and apoE; Interaction and Effect on Pathogenesis in a Mouse Model of Alzheimer's Disease

  • Funding Amount: $416,130
  • Organization Type: Academic/Nonprofit
  • Program: Drug Discovery
  • Status: Closed