(300 WORDS MAX) The current generation of drugs being tested in humans to treat Alzheimer's disease has met with limited success over the past several years. We have taken a new approach to treating Alzheimer's disease by targeting a protein termed tau that accumulates in the brains of Alzheimer's patients. We have identified a compound from southern Wax Myrtle that may be an extremely potent reducer of the tau protein. Our goal is to test whether this drug may be a viable therapeutic candidate for reducing tau in the brain and treating Alzheimer's disease.