blog

Stepping Forward in Alzheimer’s Disease Research: A Combination Therapy Approach

Chief Medical Officer at Amylyx Pharmaceuticals gives a closer look at how far they have come in their recently expanded phase 2 clinical trial, supported in part by the ADDF, which is studying a combination approach to treating people with Alzheimer’s disease.

announcements

Major Research Funding for Blood Test to Accelerate Clinical Trials for New Frontotemporal Degenerat

The Bluefield Project to Cure FTD Receives $1.2 Million Award from the Alzheimer’s Drug Discovery Foundation’s Diagnostics Accelerator

announcements

Alzheimer’s Drug Discovery Foundation Partners with Shionogi and Janssen Pharmaceuticals for its Dia

The Alzheimer’s Drug Discovery Foundation (ADDF) announced a partnership with Shionogi & Co., Ltd.  and Janssen Pharmaceuticals, Inc. as part of its  Diagnostics Accelerator, an initiative that aims to fast-track the development of novel biomarkers for the early detection of Alzheimer's disease and related dementias.

announcements

$3.2 Million in New Funding Focused on Biomarkers and Moving Toward New Therapies

These recent investments reflect the ADDF's commitment to advancing tools for early detection, with an emphasis on exploring the different pathologies associated with aging.

announcements

Alzheimer’s Drug Discovery Foundation Announces the First Diagnostics Accelerator Award Recipients

The first four awards from the first request for proposals total up to approximately $3.5 million.

announcements

$7.1 Million in New Funding Illustrates the ADDF’s Strong Support of a Diverse Pipeline

The ADDF announces $7.1 million in new investments, which reflect our strategy to advance drug discovery and clinical trials, including the development of biomarkers and prevention methods.

announcements

The ADDF Announces New Research Initiative to Advance Digital Tools for Detection for Alzheimer’s

The ADDF's Diagnostics Accelerator is seeking to fund the development of digital tools to capture quantifiable biomarkers.

announcements

ADDF Statement on Biogen and Eisai Discontinuing Trials of Aducanumab

Pharmaceuticals company Biogen and its partner Eisai announced that they will cease clinical trials for aducanumab after it was indicated the trials were unlikely to succeed.

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Top 5 Advances in 2018

In 2018 we have seen increased investments in Alzheimer's biomarkers and increased interest in prevention.

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Leading Scientists Share Exciting Research Developments at the ADDF Fall Symposium

At the ADDF's Ninth Annual Fall Symposium, Richard S. Isaacson, Michelle M. Mielke, and Mark A. Mintun discussed Alzheimer's biomarkers and prevention.

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Two Decades of Research: The ADDF’s 19th International Conference on Alzheimer’s Drug Discovery

Researchers shared updates on their approaches to developing Alzheimer's treatments at our annual conference.

announcements

19th International Conference on Alzheimer’s Drug Discovery Highlights Multiple Approaches

The conference, organized by the Alzheimer's Drug Discovery Foundation, focused on gene therapy and alternative modalities for neurodegenerative diseases, progress in developing novel drugs, as well as the need for new biomarkers.

announcements

$2.3 Million in New Funding Focused on Novel Biomarkers and Treatments

The Alzheimer's Drug Discovery Foundation (ADDF) announces funding for a novel biomarker and two Phase I clinical studies.

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Top Five Highlights from AAIC 2018

The ADDF looks back at the 2018 Alzheimer's Association International Conference.

announcements

New Coalition of Philanthropists Including Bill Gates, Leonard Lauder Commit More Than $30 Million

Bill Gates and Leonard Lauder have announced Diagnostics Accelerator, an initiative to develop new biomarkers for early detection for Alzheimer's.

announcements

$2.5 Million in New Funding Exemplifies ADDF’s Strategy

We announce $2.5 million in new funding, which reflects the comprehensive nature of our strategy to prevent and treat Alzheimer’s disease. 

announcements

Partnership with FNIH Will Drive New Biomarkers for Alzheimer’s

The ADDF has joined an initiative from the Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium that will improve diagnosis and the development of targeted therapies for Alzheimer's disease. 

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Meeting the Challenge of CTE

For CTE Awareness Day, we highlight our support of diagnostic tools and treatments for this disease. 

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Top Five Alzheimer’s Advances in 2017

Our top five advances in 2017 spotlight the substantial progress we have made toward conquering Alzheimer’s and other neurodegenerative diseases.

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Alzheimer’s Biomarkers, Explained

Learn what a biomarker is, why they matter to the ADDF, which biomarkers we have, and which ones we need.  

announcements

Three New Grants Keep Promising Programs Forging Ahead

The Alzheimer’s Drug Discovery Foundation (ADDF) announces three new investments, all of which are for programs that the ADDF previously funded.

announcements

18th Annual Conference on Alzheimer’s Drug Discovery Showcases Non-Amyloid Research

Nearly 200 academic and industry researchers came together to share updates on innovative preclinical and clinical-stage Alzheimer’s disease research at the 18th Annual Conference on Alzheimer's Drug Discovery.

announcements

New Funding Supports Blood Test for Early Alzheimer’s

The ADDF announces two new grants, including support for a blood test designed to detect Alzheimer’s disease in early stages of development and a gene therapy for frontotemporal dementia.

announcements

Latest Funding Includes Support for Innovative Clinical Trial

The ADDF announces four new grants, including support for an innovative clinical trial, two novel drug programs, and a biomarker for CTE.

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Top Five Alzheimer’s Advances in 2016

In 2016, we made great progress toward finding drugs to prevent and treat Alzheimer’s, as our top five advances demonstrate.